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Modeling cis-regulatory variation in human brain enhancers across a large Parkinson's Disease cohort

This repostory hosts all the code for the analysis and figure generation for the preprint

Repository structure

  • code to generate figures is under directory ./figures
  • analysis related to snRNA and eQTL is to be found under ./snRNA
  • analysis related to snATAC, caQTL and ASCA is under ./snATAC
  • analysis pertinent to WGS and DNA methylation is under ./WGS
  • any other analysis is under ./mixed_analysis

Data

  • raw snRNA and snATAC data will be amde available via CRN
  • processed snRNA data is available via SCope
  • processed snATAC data is available via Zenodo (bigwigs)
  • aligned WGS data is available via EGA, please refer to study numbers in the preprint

Note
We tried to include all the code, but if you notice anything missing, or you encounter any issues, feel free to open an issue!

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